Arsenal's title hopes took another blow when they were held to a 1-1 draw at home by Liverpool on Sunday after an astonishing finale in which both teams convert stoppage time penalties.
Top meets bottom in the Premier League on Saturday when leaders Chelsea make the short trip across west London to Fulham looking to consolidate their title bid and increase the relegation worries of their neighbours.
Arsenal lit up the opening day of the Premier League season with a 6-1 demolition of Everton and Didier Drogba struck in stoppage time to give Chelsea manager Carlo Ancelotti a winning start on Saturday.
'It's very difficult to play football in these circumstances within 48 hours. It's amazing for the fans around the world, everybody has the Premier League, I'm more than happy to do that but it's very hard for the players'
Tottenham Hotspur routed Bournemouth 5-0 as they leapfrogged City into second place in the league, six points behind leaders Liverpool who thrashed Newcastle United 4-0.
Nuggets of news coming from the English Premier League
Arsenal slumped to a last-gasp 2-1 Premier League defeat at relegation-threatened Brighton & Hove Albion on Saturday in a blow to the London club's chances of securing European football next season. Watford's Craig Dawson grabbed a stoppage-time equaliser with an overhead kick to earn his side a 1-1 draw with Leicester City on Saturday and a vital point in their battle for Premier League survival.
Liverpool overcame another obstacle on the path to what looks an almost certain Premier League title triumph as they chalked up a record-breaking 20th win
Carlos Tevez of Manchester City and Dimitar Berbatov of Manchester United emerged the top scorers with 20 goals in the English Premier League season, which concluded on Sunday. Arsenal's Robin van Persie, with 18 goals, was next best.
Following Carlo Ancelotti's sacking, Bikash Mohapatra takes a look at EPL managers who lost their jobs after failing to deliver this season.
A summary of Saturday's matches in the English Premier League.
The teams clash at the Etihad stadium on Sunday (1700 IST) with United three points clear of champions City.
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
Liverpool outclassed Tottenham Hotspur 4-0 at Anfield on Sunday to surge to the top of the Premier League table and raise hopes of a first English title for 24 years.
Manchester United manager Alex Ferguson predicted on Friday the Premier League title will be won by either his team or their fierce rivals Manchester City.
Brief reports of English Premier League matches on Saturday:
Mauricio Pochettino's Tottenham Hotspur can cement their status as the top dogs in the capital if they end an eight-year wait and defeat Arsenal in the North London derby on Sunday.
United down Newcastle after Saints stun Chelsea on a dramatic night in the English Premier League.
Manchester United, Chelsea, Arsenal and Liverpool switch their attention away from European glory and back to the English title race at the weekend.
Match-by-match facts and statistics ahead of the Premier League fixtures on April 28-30
The omens are good for a Chelsea side heading into Christmas top of the Premier League tree but manager Jose Mourinho does not want to give title rivals Manchester City any reason to cheer over the festive season. Check out the big games on Boxing Day.
Manchester United and Arsenal enjoyed landmark victories over Stoke City and Manchester City respectively on Sunday to stay on the coat tails of champions Chelsea in the battle for the Premier League title.
"...This club is built on what they did. It's built ... on (Bill) Shankly, (Bob) Paisley and (Joe) Fagan and all the others, but on these players... Steven Gerrard -- this club's built on, in the last 20 years, on Stevie's legs..."
Liverpool dominated the Premier League last season, winning their first domestic league title for 30 years
Manchester City can pile the pressure on Premier League leaders Chelsea for the first time this season.
Manchester United received a taste of their own medicine as a last-gasp equaliser from Tottenham Hotspur's Clint Dempsey deprived the Premier League leaders of a valuable win on Sunday.
Spending by Premier League teams has already broken last season's record and could exceed one billion pounds ($1.32 billion) by the time the transfer window closes at the end of the month.
British Sports Minister Gerry Sutcliffe has attacked spiralling wages in the Premier League.
Champions Leicester City will begin their Premier League title defence with a trip to newly promoted Hull City on August 13, according to the 2016-17 fixtures released on Wednesday.
Following is a match by match look at the English Premier League's weekend fixtures:
IMAGES from the English Premier League match played between Everton and Manchester City on Wednesday
'I'm probably one of the only ones that disagrees, for the simple fact that we only had three games that we were below standard.'
European champions Chelsea have been given the blessing of Newcastle United manager Alan Pardew to sign Senegal striker Demba Ba after his release clause was triggered on Wednesday.
Guardiola said City had plenty of options, with Gabriel Jesus the only main striker fit and ready but Ilkay Gundogan and Raheem Sterling are able to slot into the role.
Chelsea manager Jose Mourinho stoked up his war of words with Manuel Pellegrini on Monday by questioning the Manchester City manager's sums.
Chelsea striker Diego Costa has avoided disciplinary action after appearing to kick out at Liverpool's Martin Skrtel in Saturday's 3-1 defeat, according to English Football Association sources.
Two big derbies and an eventful weekend of football awaits us all...
IMAGES from the English Premier League matches played on Wednesday.
While, Reds' manager Juergen Klopp is realistic about his team being league leaders, you, dear reader, can convey your opinion by casting your vote in the poll below
Victory over Manchester United in Monday's Premier League clash would "put to bed" bitter memories of Liverpool's defeat to Jose Mourinho's Chelsea two years ago, midfielder Jordan Henderson has said.
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